There are issues in this provisional squad, and more so the squad in South Africa:
Poor fielding: Everyone knows how susceptible Indians are to poor fielding. Their poor fielders are a weakness. Yet we see poor fielders get chance after chance. There's no way any of Nehra, Praveen and Munaf should make the ODI squad, let alone all three of them. They don't add much to the game with their bowling alone, and no more than average fielders like Sreesanth and Ishant, or Vinay Kumar and Pankaj Singh, neither making this squad. This will make it difficult to take 10 wickets often.
Bowling strike rates: Some oft-criticised bowlers, notably Ishant and Sreesanth, have superior strike rates. Ishant keeps it in the low 30's often, while Sreesanth has struck under 30 since his recall. While both (especially Sree, by a wide margin) leak a lot of runs, it makes a difference when the top six is back in the hut early.
Kohli, Yuvraj and Yusuf: There's a query on which of Kohli and Yusuf play, while Yuvraj retains his place. Why not have both Kohli and Yusuf? And why should Yuvraj retain his place? Kohli has been an impressive newcomer, coming close to 50 ODIs, and maintains an impressive record. Yusuf has had a fantastic 2010 with bat and ball, and in the subcontinent, may be a pivotal selection as a #7 who can also bowl ten overs a game. Yuvraj, on the other hand, as Dhoni's preferred all-rounder, has failed with the ball, and more importantly, with bat as well. He's failed on both fronts, and has largely struggled. A stronger, more in-form side would have Kohli at three/four, Yusuf at seven, Yuvraj sitting out and the rest of the batting unchanged.
Spin choices: The emergence of Ashwin and the return of Chawla will be crucial. Chawla's form has largely been patchy, taking five wickets and scoring a century just before the announcement of the provisional squad. As a frontline spinner who can score runs, he can add a lot to the team, but he's not in the best of form. Ashwin has been a very impressive newcomer, taking two wickets a game, which is impressive, though his economy has been a tad high. He hasn't had enough chances to prune his batting ability until now, though a good choice under a strong top six. Harbhajan's strike rate, or excess of it, has been his weakness, and they can leave him out, but there's little assured from Chawla, so Bhajji and Ashwin may play together.