| Home Team | Away Team | Match Date & Time | Venue |
| Oval Invincibles Women | Manchester Originals Women | 21-07-2021 17:30:00GMT | London |
| Birmingham Phoenix Women | London Spirit Women | 23-07-2021 14:00:00GMT | Birmingham |
| Trent Rockets Women | Southern Brave Women | 24-07-2021 10:00:00GMT | Nottingham |
| Northern Superchargers Women | Welsh Fire Women | 24-07-2021 13:30:00GMT | Leeds |
| London Spirit Women | Oval Invincibles Women | 25-07-2021 10:00:00GMT | London |
| Manchester Originals Women | Birmingham Phoenix Women | 25-07-2021 13:30:00GMT | Manchester |
| Trent Rockets Women | Northern Superchargers Women | 26-07-2021 14:00:00GMT | Nottingham |
| Welsh Fire Women | Southern Brave Women | 27-07-2021 14:00:00GMT | Cardiff |
| Manchester Originals Women | Northern Superchargers Women | 28-07-2021 14:00:00GMT | Manchester |
| London Spirit Women | Trent Rockets Women | 29-07-2021 14:00:00GMT | London |
| Southern Brave Women | Birmingham Phoenix Women | 30-07-2021 14:00:00GMT | Southampton |
| Welsh Fire Women | Manchester Originals Women | 31-07-2021 10:00:00GMT | Cardiff |
| Northern Superchargers Women | Oval Invincibles Women | 31-07-2021 13:30:00GMT | Leeds |
| Birmingham Phoenix Women | Trent Rockets Women | 01-08-2021 10:00:00GMT | Birmingham |
| London Spirit Women | Southern Brave Women | 01-08-2021 13:30:00GMT | London |
| Oval Invincibles Women | Welsh Fire Women | 02-08-2021 14:00:00GMT | London |
| London Spirit Women | Northern Superchargers Women | 03-08-2021 14:00:00GMT | London |
| Birmingham Phoenix Women | Oval Invincibles Women | 04-08-2021 14:30:00GMT | Birmingham |
| Manchester Originals Women | Southern Brave Women | 05-08-2021 14:30:00GMT | Manchester |
| Welsh Fire Women | Trent Rockets Women | 06-08-2021 14:30:00GMT | Cardiff |
| Southern Brave Women | Northern Superchargers Women | 07-08-2021 14:30:00GMT | Southampton |
| Oval Invincibles Women | Trent Rockets Women | 08-08-2021 14:30:00GMT | London |
| Birmingham Phoenix Women | Welsh Fire Women | 09-08-2021 14:00:00GMT | Birmingham |
| Manchester Originals Women | London Spirit Women | 10-08-2021 14:00:00GMT | Manchester |
| Southern Brave Women | Welsh Fire Women | 11-08-2021 14:00:00GMT | Southampton |
| Northern Superchargers Women | Manchester Originals Women | 12-08-2021 14:30:00GMT | Leeds |
| Trent Rockets Women | Birmingham Phoenix Women | 13-08-2021 14:30:00GMT | Nottingham |
| Oval Invincibles Women | London Spirit Women | 14-08-2021 14:30:00GMT | London |
| Trent Rockets Women | Manchester Originals Women | 15-08-2021 14:30:00GMT | Nottingham |
| Southern Brave Women | Oval Invincibles Women | 16-08-2021 14:30:00GMT | Southampton |
| Northern Superchargers Women | Birmingham Phoenix Women | 17-08-2021 15:00:00GMT | Leeds |
| Welsh Fire Women | London Spirit Women | 18-08-2021 14:00:00GMT | Cardiff |
| Birmingham Phoenix Women | Oval Invincibles Women | 20-08-2021 14:00:00GMT | London |
| Southern Brave Women | Oval Invincibles Women | 21-08-2021 14:00:00GMT | London |
1.
